After receiving 150 mg butamirata maximum plasma concentration of the main metabolite (2-phenylbutyric acid) is achieved in about 1.5 hours and is of 6 hours. With the reappointment of the drug concentration in the blood remains linear and accumulation was observed. Hydrolysis butamirata initially to 2-phenylbutyric acid and dietilaminoetoksietanola starts in blood. These metabolites also possess antitussive activity. Like butamirata metabolites have nearly maximum degree of binding to plasma proteins, which leads to, among other things, their prolonged plasma . Metabolites are excreted mainly in the urine, the metabolites acidic largely linked to glucuronic acid.
Dry cough from any cause (including whooping cough). The suppression of cough in the pre- and postoperative period after surgery and bronchoscopy.
: Hypersensitivity to primobolan depot for sale the drug, children under the age of 2 months.
Use during pregnancy and lactation
In studies conducted in animals, there were no adverse effects on the fetus. Controlled studies in pregnant women have been conducted. Therefore Sinekod should not be used in I trimester of pregnancy. In II and III trimester use Sinekoda possible taking into account the benefits for the mother and the potential risk for ploda.Uchityvaya lack of data on the release of the active substance with the breast milk, Sinekoda appointment during lactation is not recommended.
Dosing and Administration
Inside, the food.
Children from 2 months to 1 year – 10 drops 4 times a day for
1 to 3 years – 15 drops 4 times a day for
3 years and over – 25 drops 4 times in a day.
Side effects are
skin rash, nausea, diarrhea, dizziness primobolan depot for sale (frequency less than 1%), and allergic reactions.
Overdosing Symptoms: drowsiness, nausea, vomiting, diarrhea, loss of sense of balance and blood pressure. Treatment: activated carbon, saline laxatives, maintain the function of the cardiovascular and respiratory systems.
Interaction with other drugs
Any drug interactions have not been described for butamirata.
Drops contain as sweeteners saccharin and sorbitol, therefore, can be administered to patients with diabetes mellitus.
Drops for oral administration to children in 20 ml amber primobolan depot for sale glass vial equipped with a dropper dispenser-low density polyethylene and polypropylene vial krppkami.Kazhdy with instruction is placed in a cardboard box. mastebolin